EFFECT OF NORDIHYDROGUAIARETIC ACID CROSS-LINKING ON FIBRILLAR COLLAGEN: IN VITRO EVALUATION OF FIBROBLAST ADHESION STRENGTH AND MIGRATION

Effect of nordihydroguaiaretic acid cross-linking on fibrillar collagen: in vitro evaluation of fibroblast adhesion strength and migration

Fixation is required to reinforce reconstituted collagen for orthopedic bioprostheses such as tendon or ligament replacements.Previous studies have demonstrated that collagen fibers cross-linked by the biocompatible dicatechol nordihydroguaiaretic acid (NDGA) have mechanical strength comparable to native tendons.This work focuses on investigating f

read more


Follicular regulatory T cells eliminate HIV-1-infected follicular helper T cells in an IL-2 concentration dependent manner

Follicular helper CD4+ T cells (TFH) are highly permissive Little Friend Buildings to HIV and major foci of virus expression in both untreated and treated infection.Follicular regulatory CD4+ T cells (TFR) limit TFH numbers and function in vitro and in vivo.We evaluated the hypothesis that TFR suppress HIV replication in TFH using a well-establishe

read more

Finite element simulation and experimental test of the wear behavior for self-lubricating spherical plain bearings

Abstract In this study, based on the classical Archard adhesion wear theory, a three-dimensional finite element model was established, with the aim of simulating the failure process of self-lubricating spherical plain bearings in the swinging wear condition.The results show that the self-lubricating spherical plain bearings go through two different

read more